HPLC Made to Measure: A Practical Handbook for Optimization, Stavros Kromidas

HPLC Made to Measure: A Practical Handbook for Optimization, Stavros Kromidas

The only topical HPLC book to focus on optimization, this volume addresses the needs of HPLC users who wish to constantly improve their methods, in particular in terms of throughput, accuracy and cost-effectiveness.
It covers essential aspects of optimization in general, optimization in different LC-modi, hyphenated techniques and computer-aided optimization. The whole is rounded off with a section of user reports.

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The HPLC SOlvent Guide, 2nd edition, Paul C.Sadek

The HPLC SOlvent Guide, 2nd edition, Paul C.Sadek

High-performance liquid chromatography (HPLC) is a procedure for separating components from a mixture of chemical substances; a combination of separation, identification, and quantitative measurements. Solvent selection is perhaps the most commonly overlooked parameter in HPLC. Even the most experienced analytical chemist tends to select one of three familiar solvents. The HPLC Solvent Guide provides detailed coverage of all commonly used HPLC solvents used in a wide range of separations.
This second edition of a successful title will build upon the success of the first. This is a revised and expanded edition in a field that is still growing into areas of analysis and methods.

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International Biotechnology, Bulk Chemical, and Pharmaceutical GMPs

International Biotechnology, Bulk Chemical, and Pharmaceutical GMPs, Fifth Edition

Description:

This book contains the English language texts of all GMPs, regulations, guidelines, codes, and practices implemented by national and international regulatory authorities that govern the manufacture and testing of biotechnology-derived products, active pharmaceutical ingredients, and pharmaceuticals. Prepared with the cooperation of health authorities worldwide, this resource contains the GMPs in effect in 114 countries, plus GMP regulations of the World Health Organization, including the 1996 WHO GMPs, the European Union, the Association of South East Asian Nations, and the Pharmaceutical Inspection Convention.

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PART - 1

PART - 2

Significant Pharmaceuticals Reported in US Patents

Significant Pharmaceuticals Reported in US Patents
By Thomas F. DeRosa

Description:
This book identifies the next generation of pharmaceuticals reported in US Patents. This "hands-on" title provides explicit laboratory methods for preparing the most recent and effective medications. Each entry documents the biological testing protocols used to evaluate a drug and the significance of the current treatment agent over previous methods. Pharmaceuticals are included in this review only if at least two of the following criteria were met: Effectiveness in treating an illness, Innovative, ease of preparation, synergy with existing Medications.
Pharmaceuticals are reported for 27 separate classes of illness, including;
AIDS, Alzheimer's Disease, Cardiovascular Disorders, Diabetes, Epilepsy, Hepatitis C, Osteoporosis, Obesity and Sleep Disorders.
Significant Pharmaceuticals Reported in US Patents has been designed to be used as both a reference and synthetic guide for pharmaceutical, medicinal and organic chemists and graduate students.
Researchers working in other areas will also find the information valuable as in many instances intermediates or the next generation pharmaceutical are readily convertible into other industrial products including: anti-oxidants, chemical additives, herbicides, polymer precursors, water purification agents. Clear structural depictions of reagents and chemical transformations have been supplied to permit the identification of other future applications.

* Identifies next generation pharmaceuticals
* Provides practical preparation methods for each active agent and derivatives
* Documents the analytical characterization and biological testing results of active agents.

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Transport Processes in Pharmaceutical Systems

Transport Processes in Pharmaceutical Systems
By Gordon L. Amidon, Ping I. Lee, Elizabeth M. Topp

Description:

This cutting-edge reference clearly explains pharmaceutical transport phenomena, demonstrating applications ranging from drug or nutrient uptake into vesicle or cell suspensions, drug dissolution and absorption across biological membranes, whole body kinetics, and drug release from polymer reservoirs and matrices to heat and mass transport in freeze-drying and hygroscopicity. Focuses on practical applications of drug delivery from a physical and mechanistic perspective, highlighting biological systems. Written by more than 30 international authorities in the field, Transport Processes in Pharmaceutical Systems · discusses the crucial relationship between the transport process and thermodynamic factors · analyzes the dynamics of diffusion at liquid-liquid, liquid-solid, and liquid-cultured cell interfaces · covers prodrug design for improving membrane transport · addresses the effects of external stimuli in altering some natural and synthetic polymer matrices · examines properties of hydrogels, including synthesis, swelling degree, swelling kinetics, permeability, biocompatibility, and biodegradability · presents mass transfer of drugs and pharmacokinetics based on mass balance descriptions · and more! Containing over 1000 references and more than 1100 equations, drawings, photographs, micrographs, and tables, Transport Processes in Pharmaceutical Systems is a must-read resource for research pharmacists, pharmaceutical scientists and chemists, chemical engineers, physical chemists, and upper-level undergraduate and graduate students in these disciplines.

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